Taking place before Gensomaden Saiyuki, this story offers a view of the Genjō Sanzō, Son Goku, Sha Gojyo, and Cho Hakkai before they met up.

Many years ago, humans and demons lived in harmony. But that unity ended when demons started attacking humans and plotted a mission to unleash Gyumao - an evil demon imprisoned for thousands of years. Now, Genjo Sanzo, a rogue priest, must team up with three demons - Sha Gojyo, Son Goku, and Cho Hakkai - and embark on a perilous journey to the west to stop these demons from resurrecting Gyumao and restore the balance between humans and demons on Earth.

Set in the last days of World War II, a small band of Russian soldiers led by intelligence officer Brana Vasilyeva, who is tasked with trafficking the remains of Hitler back to Stalin in Russia. En route, the unit is attacked by German ‘Werewolf’ partisans and picked off one-by-one. Brana leads her surviving comrades in a last stand to ensure their ‘cargo’ doesn’t fall into the hands of those who would see it buried in order to hide the truth forever.

On present day Earth, the brotherhood of humans and demons (youkai) has been broken. A corrupt and evil demon, Gyumao, is performing experiments that combine human science and youkai magic, causing all demons to go crazy. Now, Genjo Sanzo, a trash-taking Buddist monk, is given a mission: Deliver a sacred scroll, the Maten Scripture, to India. For the journey, he is teamed up with Son Goku, a 500-year-old demon, Sha Gojyo, a red-eyed half demon human, and Cho Hakkai, a school teacher turned demon. Together, the four of them must travel to India, but the road ahead will surely be full of speed bumps, and demon attacks.

Genjō Sanzō is a Buddhist monk sent by the Emperor on a journey to find the sacred Buddhist scriptures. One day, Sanzō meets an Earth Deity who tells him that Buddha has sent him a disciple: the mischievous Monkey Deity Son Goku, who was sealed inside of a mountain for five hundred years after wreaking havoc in Heaven! Together with the alcohol-loving playboy Cho Hakkai; the heavenly army General Sha Gojyō; and their horse, the Dragon Crown Prince Ryūba; there are plenty of adventures to be had.

The Sanzo party has always been haunted by the past. And they've always been able to deal with their ghosts. But when they enter the House Of Dougan, they may have met their match. Lured to the mysterious shrine by a beautiful girl, Sanzo, Goku, Gojyo, and Hakkai become ensnared in a trap of dangerous shikigami, murderous doppelgangers, and a malevolent monster who has destroyed his own soul for a demented purpose. Don't miss this stunningly animated full-length motion picture, starring the coolest cast of demon hunters in the history of anime!

500 years before Saiyuki, a heretic child with golden eyes is brought to Heaven and given into the reluctant care of a minor deity, Konzen, nephew of the Merciful Goddess, Kanzeon Bosatsu. Konzen eventually names him "Goku". Goku befriends two other minor gods, Marshal Tenpou and General Kenren of the Western Army of Heaven, and a boy who seems to be his age, the War Prince Nataku. Though Goku is happy in his new home, Heaven is not kind to heretics.

天地混乱的混沌时代--有一块人和妖怪共存的土地，那里是文明和信仰之源--桃源乡。 突然的异变和恐怖袭击了那土地，以往平稳生活着的的妖怪们失去了自我开始了暴走。异变的元凶是“将过去的大妖怪牛魔王给复活了”这件事。由于在这个世界上被禁忌着的科学和妖术，现在牛魔王的复活要被完成了，负波动覆盖着大地。看重这事态的天界，下达了请唐三藏去阻止牛魔王复苏实验的命令。同那不怕负波动的三人，孙悟空，沙悟浄，猪八戒一起前往遥远的西天·天竺国的旅行开始了。 与此同时，在天竺国吠登城里，牛魔王复苏实验的策划者张本人，牛魔王的情人玉面公主，向红孩儿下达了除掉三藏一行的抹杀令。红孩儿是牛魔王的儿子，为了救出被玉面公主诅咒封印起来的母亲，同仰仗他的心腹一起发起了挑战。 三藏他们能阻止牛魔王复苏实验，能使走向毁灭的桃源乡再次恢复和平吗？